Awram Herszko






Awram Herszko


Awram Herszko (ur. 31 grudnia 1937 w Karcag, Jász-Nagykun-Szolnok, Węgry) – izraelski biolog.
W roku 2004 wraz z Aaronem Ciechanowerem i Irwinem Rose’em, otrzymał Nagrodę Nobla w dziedzinie chemii za odkrycie procesu degradacji białek w komórkach, w którym bierze udział białko ubikwityna.


Dyplom ukończenia uczelni otrzymał w 1965 r., a doktorat w 1969, w Hadassah Medical School na Uniwersytecie Hebrajskim w Jerozolimie. Obecnie jest profesorem w Rappaport Family Institute for Research in Medical Sciences w Technion (Israel Institutite of Technology), w Hajfie.



Publikacje |


A. Hershko jest autorem ponad 100 publikacji naukowych[1]. Przełomowe odkrycia, które były podstawą przyznania nagrody Nobla, opisane zostały w dwóch pracach w PNAS:



  • Hershko, A., Ciechanover, A., and Rose, I.A. (1979) „Resolution of the ATP-dependent proteolytic system from reticulocytes: A component that interacts with ATP”. Proc. Natl. Acad. Sci. USA 76, pp. 3107-3110. PDF

  • Hershko, A., Ciechanover, A., Heller, H., Haas, A.L., and Rose I.A. (1980) „Proposed role of ATP in protein breakdown: Conjugation of proteins with multiple chains of the polypeptide of ATP-dependent proteolysis”. Proc. Natl. Acad. Sci. USA 77, pp. 1783-1786. PDF



Linki zewnętrzne |


  • uzasadnienie Nagrody Nobla


Przypisy |




  1. ↑ Publikacje A. Hreshki zarejestrowane w systemie PubMed















p • d • e

Laureaci Nagrody Wolfa w dziedzinie medycyny


1978: George D. Snell, Jean Dausset, Jon J. van Rood
• 1979: Roger Wolcott Sperry, Arvid Carlsson, Oleh Hornykiewicz
• 1980: César Milstein, Leo Sachs, sir James L. Gowans
• 1981: Barbara McClintock, Stanley N. Cohen
• 1982: Jean-Pierre Changeux, Solomon H. Snyder, sir James W. Black
• 1983/1984: nie przyznano
• 1984/1985: Donald F. Steiner
• 1986: Osamu Hayaishi
• 1987: Puedro Cuatrecasas, Meir Wilchek
• 1988: Henri-Gery Hers, Elizabeth F. Neufeld
• 1989: John Gurdon, Edward B. Lewis
• 1990: Maclyn McCarty
• 1991: Seymour Benzer
• 1992: M. Judah Folkman
• 1993: nie przyznano
• 1994/1995: Michael J. Berridge, Yasutomi Nishizuka
• 1995/1996: Stanley Prusiner
• 1997: Mary Frances Lyon
• 1998: Michael Sela, Ruth Arnon
• 1999: Eric Kandel
• 2000: nie przyznano
• 2001: Awram Herszko, Alexander Varshavsky
• 2002/2003: Ralph L. Brinster, Mario Capecchi, Oliver Smithies
• 2004: Robert A. Weinberg, Roger Tsien
• 2005: Alexander Levitzki, Anthony R. Hunter, Anthony J. Pawson
• 2006/2007: nie przyznano
• 2008: Howard Cedar, Aharon Razin
• 2009: nie przyznano
• 2010: Axel Ullrich
• 2011: Shin’ya Yamanaka, Rudolf Jaenisch
• 2012: Ronald M. Evans
• 2013: nie przyznano
• 2014: Nahum Sonenberg, Gary Ruvkun, Victor Ambros
• 2015: John Kappler, Philippa Marrack, Jeffrey V. Ravetch
• 2016: Lewis C. Cantley, C. Ronald Kahn
• 2017: James P. Allison











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