Wimentyna




Wimentyna (ang. vimentin) – białko cytoszkieletu eukariontów tworzące filamenty pośrednie typu III. U człowieka kodowane jest przez gen VIM w locus 10p13. Cytrulinowanej formie wimentyny przypisuje się rolę antoantygenu mogącego odgrywać rolę w patogenezie reumatoidalnego zapalenia stawów, a ocena ilościowa autoprzeciwciał przeciw cytrulinowanej wimentynie bywa stosowana pomocniczo w diagnostyce tej choroby.




Profil ekspresji genu VIM w komórkach człowieka.



Linki zewnętrzne |



  • VIMENTIN; VIM w bazie Online Mendelian Inheritance in Man (ang.)



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