Antracykliny







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Antracykliny

Antracykliny (antybiotyki antracyklinowe, ATC: L 01 DB) – grupa antybiotyków stosowanych jako leki przeciwnowotworowe. Antracykliny są stosowane w leczeniu różnorodnych nowotworów: chłoniaków złośliwych, ostrej białaczki, raka piersi, itp.


Cząsteczki antracyklin są wielofunkcyjnymi pochodnymi antrachinonu. Zazwyczaj są glikozydami zbudowanymi z daunozaminy jako reszty cukrowej oraz czteropierścieniowego aglikonu zawierającego szkielet antrachinonu z dodatkowymi grupami hydroksylowymi tworzącymi ugrupowanie hydrochinonowe sąsiadujące z grupą chinonową.



  • L 01 DB – Antracykliny i związki pochodne




  • doksorubicyna (L01DB01)







  • daunorubicyna (L01DB02)







  • epirubicyna (L01DB03)







  • aklarubicyna (L01DB04)







  • zorubicyna (L01DB05)







  • idarubicyna (L01DB06)







  • mitoksantron (L01DB07)







  • pirarubicyna (L01DB08)







  • walrubicyna (L01DB09)







  • amrubicyna (L01DB010)







  • piksantron (L01DB011)






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