Pregnanetriol
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IUPAC name (3R,5R,8R,9S,10S,13S,14S,17R)-17-[(1S)-1-hydroxyethyl]-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol | |
| Other names 5β-Pregnane-3α,17α,20α-triol | |
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ECHA InfoCard | 100.012.862 |
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| Properties | |
Chemical formula | C21H36O3 |
Molar mass | 336.52 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Pregnanetriol, or 5β-pregnane-3α,17α,20α-triol, is a steroid and inactive metabolite of progesterone.
Urine testing
Urine excretion of pregnanetriol can be measured over a period of 24 hours. Elevated urine pregnanetriol levels suggest adrenogenital syndrome. In monitoring treatment with cortisol replacement, elevated urine pregnanetriol levels indicate insufficient dosage of cortisol.[1][unreliable medical source?]
Reference ranges
For females:[1]
- 0 to 5 years: < 0.1 mg/24 hours
- 6 to 9 years: < 0.3 mg/24 hours
- 10 to 15 years: 0.1 to 0.6 mg/24 hours
- 16 years and older: 0 to 1.4 mg/ 24 hours.
For males:[1]
- 0 to 5 years: < 0.1 mg/24 hours
- 6 to 9 years: < 0.3 mg/24 hours
- 10 to 15 years: 0.2 to 0.6 mg/24 hours
- 16 years and older: 0.2 to 2 mg/ 24 hours
References
^ abc online-family-doctor.com Pregnanetriol Retrieved April 2011
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