Renanolone











































Renanolone
Renanolone.svg
Clinical data
ATC code
  • none
Identifiers
CAS Number
  • 565-99-1

PubChem CID
  • 68930
ChemSpider
  • 16736755
Chemical and physical data
Formula
C20H30O4
Molar mass 334.450 g/mol
3D model (JSmol)
  • Interactive image

Renanolone (INN), or 11-ketopregnanolone, also known as 5β-pregnan-3α-ol-11,20-dione, is a synthetic[citation needed]neuroactive steroid which is described as a general anesthetic but was never introduced for clinical use.[1] Its isomers, alfaxolone and alfadolone, are also general anesthetics, and are known to act as positive allosteric modulators of the GABAA receptor, a property which is likely the case for renanolone as well.



Chemistry


See also: List of neurosteroids


See also



  • Alfadolone

  • Alfaxolone

  • Ganaxolone

  • Hydroxydione

  • Minaxolone

  • Pregnanolone



References





  1. ^ R.A. Hill; H.L.J. Makin; D.N. Kirk; G.M. Murphy (23 May 1991). Dictionary of Steroids. CRC Press. p. 592. ISBN 978-0-412-27060-4..mw-parser-output cite.citation{font-style:inherit}.mw-parser-output q{quotes:"""""""'""'"}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-lock-limited a,.mw-parser-output .cs1-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{font-size:100%}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}



















-

這個網誌中的熱門文章

12.7 cm/40 Type 89 naval gun

圖片
12.7 cm/40 Type 89 naval gun Type 89 gun mounted on Chitose Type Naval gun anti-aircraft gun Place of origin Japan Service history In service 1932–45 Used by Imperial Japanese Navy Wars World War II Production history Designed 1928–32 Produced 1932–45 No.  built ~1500 Variants Type 88 Specifications Mass 3,100 kilograms (6,834 lb) Barrel length 5,080 millimeters (16 ft 8 in) (bore length) Shell Fixed Shell weight 20.9–23.45 kilograms (46.1–51.7 lb) Caliber 12.7-centimeter (5.0 in) Breech horizontal breech block Elevation -8° to +90° [1] Rate of fire 8-14 rounds per minute Muzzle velocity 720–725 meters per second (2,360–2,380 ft/s) Maximum firing range 9,440 meters (30,970 ft) at 90° (AA ceiling) 14,800 meters (48,600 ft) at 45° The 12.7 cm/40 Type 89 naval gun was a Japanese anti-aircraft (AA) gun introduced before World War II. It was the Imperial Japanese Navy's standard heavy AA
閱讀完整內容

Shark

圖片
For other uses, see Shark (disambiguation). Sharks Temporal range: Ludfordian-Present, 425–0 Ma PreЄ Є O S D C P T J K Pg N [1] Clockwise from top left: spiny dogfish, Japanese sawshark, whale shark, great white shark, horn shark, frilled shark, scalloped hammerhead and Australian angelshark representing the orders Squaliformes, Pristiophoriformes, Orectolobiformes, Lamniformes, Heterodontiformes, Hexanchiformes, Carcharhiniformes and Squatiniformes respectively. Scientific classification Kingdom: Animalia Phylum: Chordata Class: Chondrichthyes Subclass: Elasmobranchii Infraclass: Euselachii Superorder: Selachimorpha Orders Carcharhiniformes Heterodontiformes Hexanchiformes Lamniformes Orectolobiformes Pristiophoriformes Squaliformes Squatiniformes † Cladoselachiformes † Hybodontiformes † Symmoriida † Xenacanthida (Xenacantiformes) † Elegestolepis † = extinct Synonyms Pleurotremata Sharks
閱讀完整內容

Wiciokrzew

圖片
Wiciokrzew, suchodrzew Morfologia (wiciokrzew pospolity) Systematyka [1] Domena eukarionty Królestwo rośliny Klad rośliny naczyniowe Klad rośliny nasienne Klasa okrytonasienne Klad astrowe Rząd szczeciowce Rodzina przewiertniowate Rodzaj wiciokrzew Nazwa systematyczna Lonicera L. Sp. Pl. 173. 1 Mai 1753 Typ nomenklatoryczny Lonicera caprifolium L. [2] Multimedia w Wikimedia Commons Hasło w Wikisłowniku Kwiaty suchodrzewu pospolitego Owoce suchodrzewu pospolitego Kwiaty wiciokrzewu pomorskiego Kwiaty wiciokrzewu przewiercienia Wiciokrzew , suchodrzew ( Lonicera L.) – rodzaj roślin wieloletnich należący do rodziny przewiertniowatych ( Caprifoliaceae ). Rośliny zielne i pnące nazywane są wiciokrzewami, natomiast krzewy i niewielkie drzewa – suchodrzewami. Rodzaj liczy około 180 gatunków szeroko rozprzestrzenionych na całej półkuli północnej [3] [4]
閱讀完整內容